Exome sequencing identifies novel rheumatoid arthritis-susceptible variants in the BTNL2
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چکیده
منابع مشابه
Whole-exome sequencing identifies variants in invasive pituitary adenomas
Pituitary adenomas exhibit a wide range of behaviors. The prediction of invasion or malignant behavior in pituitary adenomas remains challenging. The objective of the present study was to identify the genetic abnormalities associated with invasion in sporadic pituitary adenomas. In the present study, the exomes of six invasive pituitary adenomas (IPA) and six non-invasive pituitary adenomas (nI...
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Rheumatoid arthritis (RA) is a highly prevalent chronic autoimmune disease. However, genetic and environmental factors involved in RA pathogenesis are still remained largely unknown. To identify the genetic causal variants underlying pathogenesis and disease progression of RA patients, we undertook the first comprehensive whole-exome sequencing (WES) study in a total of 124 subjects including 5...
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ژورنال
عنوان ژورنال: Journal of Human Genetics
سال: 2013
ISSN: 1434-5161,1435-232X
DOI: 10.1038/jhg.2013.2